The Wine Route of Dionysus passes through the Region of Eastern Macedonia and Thrace, starting from the area of Serres, where PGI Serres wines are produced. In the city of Serres, visitors can see the Byzantine acropolis and the Folklore Museum of Sarakatsanoi. Also of great interest are the Amphipolis archaeological site and its museum, Alistrati Cave, and for nature lovers – Lake Kerkini.
East of the city of Serres, the Wine Route of Dionysus continues through the vineyards of Drama and Kavala. The PGI Drama, PGI Agora and PGI Ariadne wines are produced in the Drama area. The Aggitis Cave is of great interest, while the Falakro Ski Resort is ideal for winter sports.
South of Drama, the Wine Route of Dionysus continues through the Kavala region, where PGI Kavala and PGI Pageo wines are produced. Starting at the beautiful city of Kavala, where points of interest include the medieval aqueduct, the Kavala Castle, the archaeological museum and the Tobacco Museum, visitors can also see located a short distance away the ancient city and the early Christian city of Philippoi, Anaktaropolis of Nea Peramos and the Tower of Apollonia. Small boats come and go regularly from Keramoti or Peramos to magical Thassos, where the PGI Thassos wines are produced.
The Wine Route of Dionysus continues eastward through the Xanthi region where most of the wine-making activity is located in Abdera, where the PGI Abdera wines are produced. Visitors to the area can go to the archaeological site of Abdera, to Byzantine Polystylo and to the archaeological museum. In the city of Xanthi, the section of the old city of Xanthi is particularly appealing and it is where the Festivals of the Old City take place annually.
Moving eastward, the Wine Route of Dionysus reaches the Rodopi region, where most of the wine-making takes place in Maronia. The vineyard there produces the PGI Ismaros wines which have a long history originating in ancient Maronia. In Komotini, visitors can see the archaeological museum, the Komotini Imaret and the Roma Basketry Museum. Sites in the greater area include Maximianoupolis, Anastasioupolis and Mount Papikion.
The Wine Route of Dionysus concludes in the region of Evros, where PGI Evros wines are produced. In Alexandroupoli, places to visit include the Ethnological Museum of Thrace, the Museum of Natural History and the Historical Museum of Alexandroupoli. Further to the east is the Evros River Delta, while going north, some of the main sites in geographical order include: in the Feres area, the monastery of Kosmosotira (Our Lady Saviour of the World); in the Soufli area, the Dadia National Park and the Silk Museum; in the Didimoticho area, the Castle of Didimoticho, Plotinopolis and Pythion Castle; and in the Orestiada area, the Folklore and History of Art Museum of Orestiada and the burial tumulus of Mikri Doxipara-Zoni. From Alexandroupoli, it is possible to cross to the beautiful island of Samothrace.