At the time of Alexander the Great’s death (323 BC), winemaking prosperity in the south was exceptional. To be more precise, by that time, Greek winemaking and wine commerce had already shifted their center of interest towards that area of the known world of the time: The scarce and exorbitantly priced wines produced on the small islands of the Aegean could hardly meet the needs of Alexander the Great’s campaigns and armies, let alone the demand by the markets that were just opening up. Thus, intense winemaking activities began taking place, mainly, on Rhodes, Kos, Cyprus, and Asia Minor.