With the onset of Roman rule in Greece, the center of wine commerce, with the exception of the south Aegean, shifted to the eastern Mediterranean. Macedonia, which had already become a Roman province, continued to produce highly acclaimed wines, as did the islands of the north Aegean which, however were past their heyday. Due to its geographical position and its abounding natural resources, Crete soon became the wine target the Romans set their sights at. From 146 BC on, wine came under the control of the Romans.